The Oracle E-Business Suite applications run on top of the vendor's flagship Oracle Database software. First released in 2001, E-Business Suite was Oracle's first full bundle of ERP and CRM applications; it remains the most widely used line of business applications in the company's product portfolio, despite subsequent acquisitions of various other application vendors and technologies, including JD Edwards, PeopleSoft and Siebel.

Like rival offerings from vendors such as SAP and Microsoft, Oracle E-Business Suite was designed to help users manage global businesses, improve decision making, reduce costs and increase corporate performance. E-Business Suite contains application modules that support different aspects of CRM, ERP and SCM operations, including customer service management, financial management, human capital management, project portfolio management, procurement, and value chain planning and execution. Oracle also has pre-integrated its business intelligence applications with E-Business Suite to provide EBS users with BI and analytics capabilities.